Navigating the Psychedelic Frontier
Advancements in Therapeutics & Research
Study participants from prior psilocybin trials talk about how their experiences.
Publications in
Medical Journals
Numerous peer-reviewed journals have featured thousands of articles focusing on psilocybin clinical research. Findings from these studies indicate psilocybin can be safely administered within medical settings. The emerging research holds promise for the potential of psilocybin therapy in alleviating depression and anxiety among individuals confronting life-threatening illnesses.

Grob CS, Danforth AL, Chopra GS, Hagerty M, McKay CR, Halberstadt AL, Greer GR. Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer. Arch Gen Psychiatry. 2011 Jan;68(1):71-8. doi: 10.1001/archgenpsychiatry.2010.116.
Ross S, Bossis A, Guss J, Agin-Liebes G, Malone T, Cohen B, Mennenga SE, Belser A, Kalliontzi K, Babb J, Su Z, Corby P, Schmidt BL. Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial. J Psychopharmacol. 2016 Dec;30(12):1165-1180. doi: 10.1177/0269881116675512.
Griffiths RR, Johnson MW, Carducci MA, Umbricht A, Richards WA, Richards BD, Cosimano MP, Klinedinst MA. Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. J Psychopharmacol. 2016 Dec;30(12):1181-1197. doi: 10.1177/0269881116675513.
Agin-Liebes, G. I., Malone, T., Yalch, M. M., Mennenga, S. E., Ponté, K. L., Guss, J., … & Ross, S. (2020). Long-term follow-up of psilocybin-assisted psychotherapy for psychiatric and existential distress in patients with life-threatening cancer. Journal of Psychopharmacology, 34(2), 155-166. https://doi.org/10.1177/0269881119897615
Swift, T. C., Belser, A. B., Agin-Liebes, G., Devenot, N., Terrana, S., Friedman, H. L., … & Ross, S. (2017). Cancer at the dinner table: experiences of psilocybin-assisted psychotherapy for the treatment of cancer-related distress. Journal of Humanistic Psychology, 57(5), 488-519. https://journals.sagepub.com/doi/pdf/10.1177/0022167817715966
Bossis, A. P. (2021). Psilocybin, spirituality, and palliative care: Research and implications. Alternative and Complementary Therapies, 27(1), 14-17. https://www.liebertpub.com/doi/10.1089/act.2020.29309.apb
Grob, C.S, Bossis, A.P. and Griffiths, R.R. Use of the classic hallucinogen psilocybin for treatment of existential distress associated with cancer: in B. Carr and J. Steel (Eds.), Psychological Aspects of Cancer. 2nd Edition, New York, Springer, 2022. https://link.springer.com/chapter/10.1007/978-3-030-85702-8_5